Personalised medicine in action

Back in February, the National Institute for Health and Care Excellence (NICE) published their official evidence-based recommendations for patients diagnosed with colorectal cancer (CRC) to be tested for Lynch syndrome (LS), a hereditary form of the disease. Colorectal cancer, also called bowel cancer, is the fourth most common cancer in the UK, and though LS accounts for no more than 5% of...

Using genomics in complex diseases: do health professionals need new skills?

Genetic variants play a significant role in common diseases, especially cancer. Yet evidence for the inclusion of genetic profiling in population health screening and prevention programmes has been weak, and risk assessment currently tends to focus solely on age, sex, family history and certain lifestyle factors  (for example, smoking).