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Project to develop new genetic tools to explore disease
Sources: Press release, Medical News Today
A Canadian study will create new and improved resources for investigating the role of genetic mutations in neurological diseases.
CanEuCre project researchers will develop resources that use the cre-recombinase (Cre) gene to induce novel mutations and model disease states affecting the brain, spinal cord and eye in mice. The work is funded by Genome BC, and links with the EU-funded EUCOMM Tools study, part of international work in developing mouse models of human disease by genetic manipulation.
Lead investigator Dr Elizabeth of the Centre for Molecular Medicine and Therapeutics said that the project would “put in the hands of scientists worldwide the tools needed to explore what every gene in the genome does, both under normal circumstances, and when diseased". It is hoped that the resources will ultimately be used for applied research developing therapeutics for neurological disorders such as Parkinson’s and Alzheimer’s diseases