Babies born following IVF with arrayCGH genetic egg screening

21 October 2010

The birth of twin girls in Germany and a boy in Italy have now been announced as the first from a pan-European pilot study, conducted by the European Society of Human Reproduction and Embryology (ESHRE). The study was a ‘proof-of-principle’ assessment of the utility of this screening method in increasing live birth rates following IVF treatment. A large-scale international clinical trial is expected to start in 2011.

ArrayCGH oocyte screening is likely to be most useful where the rate of chromosomal abnormality is higher than average, such as in older women or those with a history of unsuccessful IVF. It may also be of particular importance in countries such as Germany where genetic analysis is permissible for egg cells but not embryos.

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