New reviews and commentaries, 17 July 2006

17 July 2006

Clarifying the mechanics of DNA strand exchange in meiotic recombination. Neale MJ and Keeney S (2006) Nature 442(7099), 153-8. Review (PubMed).

Gene regulation: a finger on the mark. Becker PB (2006) Nature 442(7098), 31-2. News and views piece on current understanding of how chromatin (DNA packaged with histone proteins in the cells) is involved in the regulation of gene expression (PubMed).

Advances in genetics: what are the benefits for patients? Munnich A (2006) J Med Genet. 43(7), 555-6. Commentary on the current and future impact of technological advances on improving treatment for genetic diseases, particularly monogenic diseases (PubMed)

Oesophageal atresia, tracheo-oesophageal fistula, and the VACTERL association: review of genetics and epidemiology. Shaw-Smith C (2006) J Med Genet. 43(7), 545-54. Review (PubMed).

Family history in colorectal cancer surveillance strategies. Hakama M (2006) Lancet 368(9530), 101-3. Discussion (PubMed). See also corresponding journal club article.

Evolutionary Genetics: Is brain evolution still continuing in modern humans? Stern Rand Woods CG (2006) Eur J Hum Genet. 14(7), 799-800. Commentary on the controversy aroused by recent papers proposing that novel haplotypes of the microcephalin and ASPM genes may be involved in determination of cognitive traits, and that the relatively recent appearance of these haplotypes may mean that the brain is continuing to evolve (PubMed).

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