New Reviews and Commentaries - 3rd October 2005

3 October 2005

The Use of Racial, Ethnic, and Ancestral Categories in Human Genetics Research. NHGRI Race, Ethnicity, and Genetics Working Group (2005) Am. J. Hum. Genet. 77, 519-532. Review looking at concepts of race and ethnicity, and how the use of such categorisation in genetics can imply that differences between groups are solely biologically (as opposed to socially or environmentally) mediated. The authors call for careful investigation of traits associated with different ethnic groups as an essential component of disease research.

Reforming research ethics committees. BMJ (2005) 331, 587-588. Editorial commenting on the UK Department of Health report on the operation of NHS research ethics committees.

Genetic linkage studies. Teare MD and Barrett JH (2005) Lancet 366, 1036-1044. Second in a series of summary pieces on aspects of genetic epidemiology.

Massively parallel sequencing. Rogers Y and Venter JC (2005) Nature 437, 326-327. News and views article on a novel form of DNA sequencing system reported in the same issue, which is around 100 times faster than current advanced sequencing methods, looking at advantages and limitations.

Beta-Thalassemia. Rund D and Rachmilewitz E (2005) N. Engl. J. Med. 353, 1135-1146. Review article including a section on progress in prenatal diagnosis.

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