Selected new reviews and commentaries, 1 November 2009

1 November 2009

Gene therapy deserves a fresh chance
Nature. 2009 Oct 29;461(7268):1173.

The DNA-damage response in human biology and disease.

Jackson SP, Bartek J. Nature. 2009 Oct 22;461(7267):1071-8.

Genetics of motor neuron disorders: new insights into pathogenic mechanisms
Dion PA, Daoud H, Rouleau GA. Nat Rev Genet. 2009 Nov;10(11):769-82.

Human genetics: Hit or miss?
Chi KR. Nature. 2009 Oct 8;461(7265):712-4.

Finding the missing heritability of complex diseases.
Manolio TA et al. Nature. 2009 Oct 8;461(7265):747-53.

Genomics of Emerging Infectious Disease
Collection of open-access articles on how genomics can revolutionize our understanding of emerging infectious disease.

Public access to genome-wide data: five views on balancing research with privacy and protection
P3G Consortium et al. PLoS Genet. 2009 Oct;5(10):e1000665. Epub 2009 Oct 2.

Megascience. 'Omics data sharing.
Field D et al. Science. 2009 Oct 9;326(5950):234-6.

China: Public Health Genomics
Zheng S, Song M, Wu L et al. Public Health Genomics. 2009 Sep 22. [Epub ahead of print]

Genetics. Life after GWA studies.
Dermitzakis ET, Clark AG. Science. 2009 Oct 9;326(5950):239-40.

The era of genome-wide association studies: opportunities and challenges for asthma genetics.
Zhang G, Goldblatt J, Lesouëf P. J Hum Genet. 2009 Oct 9 [Epub ahead of print]

Alzheimer's disease beyond APOE
van Es MA, van den Berg LH. Nat Genet. 2009 Oct;41(10):1047-8.

Genome-wide association studies in Alzheimer's disease.
Bertram L, Tanzi RE. Hum Mol Genet. 2009 Oct 15;18(R2):R137-45.

Looking for a target on every tumor
Kaiser J. Science. 2009 Oct 9;326(5950):218-20.

DNA damage, aging, and cancer.
Hoeijmakers JH. N Engl J Med. 2009 Oct 8;361(15):1475-85.

The genetics of inbreeding depression.
Charlesworth D, Willis JH. Nat Rev Genet. 2009 Nov;10(11):783-96.

Rethinking how DNA methylation patterns are maintained.
Jones PA, Liang G. Nat Rev Genet. 2009 Nov;10(11):805-11.

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