Selected new reviews and commentaries, 6 January 2009

6 January 2009

Helsinki discords: FDA, ethics, and international drug trials.
Kimmelman J, Weijer C, Meslin EM. Lancet 2009 Jan 3; doi: 10.1016/s01406736(08)61936-4.

A favourable (molecular) signal for personalised medicine.

Genotype-phenotype databases: challenges and solutions for the post-genomic era.

Thorisson GA, Muilu J, Brookes AJ. Nat Rev Genet. 2009 Jan;10(1):9-18.

Integrative biology - a strategy for systems biomedicine.

Liu ET. Nat Rev Genet. 2009 Jan;10(1):64-8.

A scientific approach to policy.Alberts B.Science. 2008 Dec 5;322(5907):1435.

Is the grass greener? From health statistics to policy decisions.Crook ED, Hundley TJ. Lancet. 2009 Dec 20;372(9656):2090-2. Epub 2008 Nov 17.

Progress and challenges in genome-wide association studies in humans.Donnelly P.Nature. 2008 Dec 11;456(7223):728-31.

Cohort studies and the genetics of complex disease.
Manolio TA. Nat Genet. 2009 Jan;41(1):5-6.

Detecting shared pathogenesis from the shared genetics of immune-related diseases.
Zhernakova A, van Diemen CC, Wijmenga C. Nat Rev Genet. 2009 Jan;10(1):43-55.

Breast cancer susceptibility: current knowledge and implications for genetic counselling.
Ripperger T, Gadzicki D, Meindl A, Schlegelberger B. Eur J Hum Genet. 2008 Dec 17.

Legal update: living with the Genetic Information Nondiscrimination Act.
Erwin C. Genet Med. 2008 Dec;10(12):869-73.

Prostate cancer genomics: towards a new understanding.

Witte JS. Nat Rev Genet. 2008 Dec 23.

Molecular diagnosis of Fragile X syndrome.Sofocleous C, Kolialexi A, Mavrou A. Expert Rev Mol Diagn. 2009 Jan;9(1):23-30.

Obama transition. A fresh start for embryonic stem cells.
Holden C. Science. 2008 Dec 12;322(5908):1619.

Analysis: Secretary's Advisory Committee on Genetics, Health, and Society Report falls short.Klein RD. Hum Pathol. 2008 Dec 10.

Shared Genetic Risk Factors for Type 1 Diabetes and Celiac Disease.
Plenge RM. N Engl J Med. 2008 Dec 25;359(26):2837-8.
Searching for targets of viral microRNAs.
Whitby D. Nat Genet. 2009 Jan;41(1):7-8.
Evaluating signatures of sex-specific processes in the human genome.
Bustamante CD, Ramachandran S. Nat Genet. 2009 Jan;41(1):8-10.
Protein demethylation required for DNA methylation.
Hotz HR, Peters AH. Nat Genet. 2009 Jan;41(1):10-1.
The many roles of histone deacetylases in development and physiology: implications for disease and therapy.
Haberland M, Montgomery RL, Olson EN. Nat Rev Genet. 2009 Jan;10(1):32-42.

RNA Seq: a revolutionary tool for transcriptomics.

Wang Z, Gerstein M, Snyder M. Nat Rev Genet. 2009 Jan;10(1):57-63

In tough times, personalized medicine needs specific partners.

Ballantyne C. Nat Med. 2008 Dec;14(12):1294.

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