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Coming soon
Next steps in the sequence, the PHG Foundation report on the clinical implications of whole genome sequencing will be launched on 24th October – available online from 25th October.
Genome sequencing
Clinical genomics has been a major theme over the last month, including plans to offer whole genome sequencing to the Faroe Islands population, great enthusiasm for personal genome sequencing among scientists, and discussion of clinical applications and concerns.
Clinical genome sequencing - a glimpse of the future?
Poll on interest in personal genome information
Curiosity driving personal genetic testing among scientists
Should researchers reveal genetic findings?
World first as genome sequencing offered to entire Faroe islands
Policy and regulation
Germany has adopted a relatively liberal stance on animals containing human material, whilst major medical research bodies have criticised excessively bureaucratic European regulations; we also review European and Asian developments in rare disease policies.
International approaches to rare diseases
Clinical trial rules 'hampering research'
Germany rules on ethics of human-animal hybrids
Newborn screening and birth defects
Egypt has unveiled a huge new national newborn screening programme and the US is set to adopt a congenital heart disease screen in their programme, whilst international targets in improving maternal and child health have not be fulfilled.
Egyptian newborn screening laboratory is world's largest
Millennium Development Goals prove too ambitious
Universal newborn screening for congenital heart disease in US
Stem cells and clinical research
The UK’s first clinical trial using human embryonic stem cell therapies is to go ahead for patients with an eye disease; a new approach to genetic liver disease therapy has been unveiled. Successful creation of human embryos by cloning has raised worries over the sources of human eggs used.
Combined stem cell and gene therapy for liver disease
UK to trial use of human embryonic stem cells
Human cloning: scientific progress and ethical concerns
Research projects and databases
Major new projects have launched this month in human epigenomics and epigenetics, as well as a mouse phenotyping initiative which it is hoped will support medical research. The UK’s first dedicated tissue bank for brain tumours has also opened to researchers.
Blueprint for success in human epigenomics?
New focus on epigenetics for Structural Genomics Consortium
UK's first brain tumour tissue bank established
Launch of mouse phenotyping project
Genetics and disease
Research published in recent weeks has ranged widely from a potential new biomarker for Huntington’s disease and insight to the genetic basis of motor neuron disease and BRCA1-linked cancer, through to sequencing of the historical bubonic plague pathogen and association of new genes with coronary artery disease.
Genetic cause of neurodegenerative disorders unravelled
Earlier diagnosis of BRCA-cancers in younger generations
Insights into the function of BRCA1
A new target for chronic pain?
Grandmother of modern plague sequenced
Master switch in diabetes discovered
Genetic biomarker for Huntington's disease identified
5 new genes linked to coronary artery disease
Personalization of asthma therapy?
New reviews and commentaries
Our selection of interesting recent articles
Other news
BRCA2 mutation carriers have better ovarian cancer survival rates
Vegetables and fruit ‘counteract heart risk genes’
Genetic cause of severe hypoglycaemia found
New mouse model for autism
Potential new drug for mixed-lineage leukaemia
South Korea plans boost to stem cell research
New genes revealed for Type 1 diabetes
Collaborative mechanisms for IP management in the life sciences
Genetic ‘hypermutations’ drive tumour resistance to therapy
Gene could hold key to reversing diabetes
Genetic Alliance launches Baby’s First Test
New study of neurodevelopment in rare disorders.
Obama signs patent-approval law
Scientists appeal on embryonic stem cell funding
Genetic link between schizophrenia and bipolar disorder
Several common genetic variants associated with mental illness
Animals with human material
Gene helps explain a third of inherited ALS cases
Aboriginal Australian ancestry revealed by genome analysis
Broad support for European Institute of Innovation and Technology
Embryonic stem cells identical to human iPS cells
Will we all be tweaking our genetic code?
Welcome to the genomic revolution (TED talk)
Cardiac gene therapy shows promise
Embryonic stem cells may permit genetic screening
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