PHG Foundation | Monthly news round-up


March 2014


Top story this month

Following the first partner meeting of the Global Alliance for Genomics & Health in London, PHG Foundation Director Dr Hilary Burton emphasises the importance of developing the clinical as well as research interfaces.
Global Alliance for Genomics & Health: losing sight of health?

Opinion: China moves to control medical genetic testing

In the last month China has moved from having no regulation of genetic testing to a strict regime requiring approval for all medical applications; Dr Ron Zimmern and Dr Philippa Brice consider the potential motivations behind this change.
China imposes restrictive regulation of genetic testing

Genetic testing and public health

Non-invasive prenatal testing (NIPT) is shown to outperform current screening for aneuploidy in the general pregnant population in the US, and a genetic test for human papilloma virus is recommended for cervical cancer screening in the UK. Prospects for the use of genetic testing in prostate cancer screening, diabetes diagnosis and the management of obesity are also highlighted.
Non-invasive prenatal testing outperforms screening
HPV genetic test recommended for cervical cancer screening
Prospects for genetic risk screening in prostate cancer
The value of genetic testing for diabetes
The impact of genetics on fried food consumption and obesity

Personalised medicine

A new discussion paper looks at the potential and problems of clinical genome sequencing. Gene therapy is boosted by a promising new approach to HIV treatment, but there is gloom for regenerative medicine as further doubts are cast on the recently revealed ground-breaking technique for stem cell creation.
Uncertainty is a problem for clinical whole genome sequencing
Acid-bath stem cell creation method: hoax or hiatus?
Promising results from HIV gene editing therapy

Policy and regulation

Both sides of the Atlantic have been examining the issue of the mitochondrial transfer cloning technique, as the UK Department of Health consults on regulation to support clinical and economic benefits and the US FDA reviews the science.
UK aims to create health and wealth by mitochondrial transfer
US regulator considers science of mitochondrial replacement

Rare diseases

Appropriately for a month that included Rare Disease Day, development of a national strategy for health services in England has moved forward slightly and Canada has launched a collaborative initiative to support improved diagnosis. The UK has also unveiled plans to allow earlier access to potential new treatments.
New Canadian rare diseases portal launched
NHS England outlines plans for rare diseases
Early access to innovative medicines for UK patients

External news and opinion

Hacking the genetic code
The triumph of genomic medicine
Google invites geneticists to upload DNA data to cloud
Researchers discover two new genetic regions for bipolar disorder
Genetic entrepreneur sets his sights on ageing and death
Initiative formed to battle neurofibromatosis
Young women with BRCA1 mutation 'should remove ovaries earlier'
DNA analysis finds new target for diabetes drugs
Court denies Myriad Genetics' motion to block rival
The $1000 genome, what does it mean for patients?
Calls for more research on the ethics of genetic testing in children
Easy test. Tough answers
Prenatal DNA tests should be new standard






Last Updated: 16 May 2013