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		<title>Articles from the PHG Foundation Newsletter</title>
		<link>http://www.phgfoundation.org/newsletter</link>
		<description>Articles from the PHG Foundation Newsletter</description>
		<copyright>PHG Foundation</copyright>
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			<title>Genetic predictor of Parkinson's disease progression</title>
			<link>http://www.phgfoundation.org/news/month/05/2012/#story_11909</link>
			<pubDate>Tue, 22 May 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ Research published in PLoS One suggests that Parkinson&amp;rsquo;s disease patients with a particular gene variant are likely to experience faster decline in motor function. Parkinson&amp;rsquo;s disease is characterised by progressive deterioration of motor skills, but the rate and the degree of functional ... ]]></description>
		</item>
				<item>
			<title>Gene linked to memory capacity and risk of PTSD</title>
			<link>http://www.phgfoundation.org/news/month/05/2012/#story_11869</link>
			<pubDate>Wed, 16 May 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ A study published in Proceedings of the National Academy of Sciences&amp;nbsp;has identified a gene that influences both the capacity to form memories and an individual&amp;rsquo;s susceptibility to post-traumatic stress disorder (PTSD). PTSD can be highly debilitating: symptoms may include repeatedly re-ex ... ]]></description>
		</item>
				<item>
			<title>Sequencing provides more evidence for role of sun in skin cancer</title>
			<link>http://www.phgfoundation.org/news/month/05/2012/#story_11856</link>
			<pubDate>Fri, 11 May 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ A study published in Nature&amp;nbsp;appears to confirm the role of exposure to ultraviolet light as a cause of melanoma, as well as implicating a new region of gene mutations as a factor. Melanoma is not the most common form of skin cancer, but is the most dangerous because of its tendency to metastasi ... ]]></description>
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			<title>Different diseases may share genetic links</title>
			<link>http://www.phgfoundation.org/news/month/05/2012/#story_11784</link>
			<pubDate>Thu, 03 May 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ Genetic research is shedding light on how apparently very different diseases may be more closely related than previously supposed.  &amp;nbsp;  Determining the genetic causes and contributions to different diseases is important for understanding how diseases arise, and how it may be possible to prevent  ... ]]></description>
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				<item>
			<title>Epigenetic test could inform breast cancer risk prediction</title>
			<link>http://www.phgfoundation.org/news/month/05/2012/#story_11771</link>
			<pubDate>Wed, 02 May 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ UK researchers have published data in the journal Cancer Research showing a strong link between an epigenetic modification of a gene in white blood cells and the risk of breast cancer.  &amp;nbsp;  The Breast Cancer Campaign funded scientists examined methylation levels in the ATM gene among 1380 women, ... ]]></description>
		</item>
				<item>
			<title>Sequencing can boost genetic diagnosis for learning disability</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11759</link>
			<pubDate>Mon, 30 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ Efforts to identify genetic causes of learning disability suggest much higher rates of diagnosis may be feasible.  &amp;nbsp;  Learning disability and developmental delay are relatively common, affecting 1-3% of the general population, and genetic causes can underlie up to around half of all cases, depe ... ]]></description>
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				<item>
			<title>Fat mice provide genetic clues to obesity puzzle</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11653</link>
			<pubDate>Thu, 12 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ A new study published in Nature Medicine provides clues as to how a gene mutation may lead to obesity.&amp;nbsp;  &amp;nbsp;  Mutations in the brain-derived neurotrophic factor gene (BDNF) have previously been shown to cause obesity in mice and have been identified in severely obese children.&amp;nbsp;Genome-wi ... ]]></description>
		</item>
				<item>
			<title>More pieces in the genetic puzzle of autism</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11633</link>
			<pubDate>Wed, 11 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ Whole exome-sequencing studies have identified a large number of mutations associated with significantly increased risk of autism spectrum disorder (ASD).  &amp;nbsp;  Published in the journal Nature, three different papers report the findings of hundreds of independent de novo mutations in sporadic (no ... ]]></description>
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			<title>Dispute over clinical value of genome sequencing</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11600</link>
			<pubDate>Sat, 07 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ A new paper published in Science Translational Medicine says that the capacity of personal genome sequencing to predict (and direct steps to prevent) common diseases is limited.&amp;nbsp;The Predictive Capacity of Personal Genome Sequencing&amp;nbsp; reports the examination ofhealth data from thousands of i ... ]]></description>
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			<title>Epigenetic links with schizophrenia risk</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11551</link>
			<pubDate>Mon, 02 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ Studies into schizophrenia are revealing new insights into the genetic and environmental influences on the disease.  Scientists have previously found that genetic factors account for about 50% of the risk of developing schizophrenia, leaving the other 50% to external or environmental factors, the ef ... ]]></description>
		</item>
				<item>
			<title>Genetic insight to some cases of severe flu</title>
			<link>http://www.phgfoundation.org/news/month/03/2012/#story_11508</link>
			<pubDate>Mon, 26 Mar 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ New research has revealed a possible genetic cause for unusually severe cases of influenza (flu).  &amp;nbsp;  Writing in the journal Nature, scientists report that a variant ofthe IFITM3 gene was more common in people hospitalised for flu than in the general population. The variant is present in around ... ]]></description>
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				<item>
			<title>'Granny gene' can affect babies' birthweight</title>
			<link>http://www.phgfoundation.org/news/month/03/2012/#story_11502</link>
			<pubDate>Mon, 26 Mar 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ New research has revealed that a gene variant inherited from mothers may affect the size of newborn baby children or grandchildren.  &amp;nbsp;  The PHLDA2 gene was already linked with reduced birthweight, with the suggestion that this function increased the chance of the mother surviving childbirth, in ... ]]></description>
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			<title>More evidence linking telomeres and early ageing</title>
			<link>http://www.phgfoundation.org/news/month/03/2012/#story_11423</link>
			<pubDate>Mon, 12 Mar 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ Understanding more about the role of telomeres in both normal ageing and disease risk is important &amp;ndash; but as many other factors (including epigenetics) are likely to be involved, commercial telomere testing as a guide to health is probably still premature.  &amp;nbsp; ]]></description>
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			<title>New breast cancer gene identified</title>
			<link>http://www.phgfoundation.org/news/month/03/2012/#story_11366</link>
			<pubDate>Fri, 02 Mar 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ If these findings are reproduced in other populations, genetic testing for inherited causes of breast cancer might need to further expand to include mutations in this new gene, as well as other genes already implicated in the disease.&amp;nbsp;&amp;nbsp; ]]></description>
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			<title>What's normal? Identifying harmful human gene inactivation.</title>
			<link>http://www.phgfoundation.org/news/month/02/2012/#story_11332</link>
			<pubDate>Tue, 28 Feb 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ Researchers have launched a new catalogue of &amp;lsquo;loss-of-function&amp;rsquo; (LoF) gene variants, which suggests that healthy individuals may have multiple completely inactive genes with no ill effects.  Part of the 1000 Genomes Project (see previous news) based at the Wellcome Trust Sanger Institute ... ]]></description>
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			<title>Probing the genetic risk of Alzheimer's disease</title>
			<link>http://www.phgfoundation.org/news/month/02/2012/#story_11268</link>
			<pubDate>Mon, 20 Feb 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ A new study on the genomics of Alzheimer&amp;rsquo;s disease will look at genome sequences from 1000 Alzheimer&amp;rsquo;s patients, as well as healthy controls.  &amp;nbsp;  The New York Genome Center (NYGC), a collaborative genome sequencing and informatics initiative that brings together academic and clinica ... ]]></description>
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			<title>Type 2 diabetes genes identified in multiple ethnic groups</title>
			<link>http://www.phgfoundation.org/news/month/02/2012/#story_11237</link>
			<pubDate>Wed, 15 Feb 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ Research has linked four new genes to risk of type 2 diabetes.  &amp;nbsp;  Published in the&amp;nbsp;American Journal of Human Genetics, the research examined genetic variants in 2,000 genes involved in cardiac and metabolic function. Data came from multiple studies involving more than 17,000 people with t ... ]]></description>
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			<title>Common form of Y-chromosome linked to heart disease risk</title>
			<link>http://www.phgfoundation.org/news/month/02/2012/#story_11229</link>
			<pubDate>Sat, 11 Feb 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ A major new mechanism by which increased risk of coronary artery disease (CAD) is passed from fathers to sons has been identified.  &amp;nbsp;  Reporting in The Lancet, researchers who studied over 3000 men say they have identified a common Y-chromosome haplogroup that increases the risk of CAD by about ... ]]></description>
		</item>
				<item>
			<title>Genetic link between melatonin and diabetes</title>
			<link>http://www.phgfoundation.org/news/month/02/2012/#story_11176</link>
			<pubDate>Fri, 03 Feb 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ New research published in Nature Genetics has identified a substantially increased risk of type 2 diabetes for people with rare genetic mutations in the melatonin receptor 1B gene, MTNR1B.  &amp;nbsp;  Melatonin is known as the &amp;lsquo;body clock&amp;rsquo; hormone; it controls the cycle of sleep and wakeful ... ]]></description>
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				<item>
			<title>Genes may help brains age better</title>
			<link>http://www.phgfoundation.org/news/month/01/2012/#story_11072</link>
			<pubDate>Tue, 24 Jan 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ Taking advantage of an unusual database, researchers have been able to estimate the influence genes have on changes in our cognitive ability over a lifetime. &amp;nbsp;&amp;nbsp;The database holds results of intelligence tests taken by a cohort of over 65 year olds in Scotland. What makes the database speci ... ]]></description>
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