<?xml version="1.0" encoding="iso-8859-1"?>
	<!-- 
		XML Comment inserted to enable XSL in Firefox 2.0 
		XML Comment inserted to enable XSL in Firefox 2.0 
		XML Comment inserted to enable XSL in Firefox 2.0 
		XML Comment inserted to enable XSL in Firefox 2.0 
		XML Comment inserted to enable XSL in Firefox 2.0 
		XML Comment inserted to enable XSL in Firefox 2.0 
		XML Comment inserted to enable XSL in Firefox 2.0 
		XML Comment inserted to enable XSL in Firefox 2.0 
		XML Comment inserted to enable XSL in Firefox 2.0 
		XML Comment inserted to enable XSL in Firefox 2.0 
	-->
	<?xml-stylesheet type="text/xsl" href="http://www.phgfoundation.org/public/templates/foundation_corp/xsl/newsletter.xsl"?>
	<rss version="2.0">
		<channel>
		<title>Articles from the PHG Foundation Newsletter</title>
		<link>http://www.phgfoundation.org/newsletter</link>
		<description>Articles from the PHG Foundation Newsletter</description>
		<copyright>PHG Foundation</copyright>
		<list_type>news</list_type>
		<customJS>http://www.phgfoundation.org/rss/newsletter.xml?format=js</customJS>
		
				<item>
			<title>Genetic predictor of Parkinson's disease progression</title>
			<link>http://www.phgfoundation.org/news/month/05/2012/#story_11909</link>
			<pubDate>Tue, 22 May 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ Research published in PLoS One suggests that Parkinson&amp;rsquo;s disease patients with a particular gene variant are likely to experience faster decline in motor function. Parkinson&amp;rsquo;s disease is characterised by progressive deterioration of motor skills, but the rate and the degree of functional ... ]]></description>
		</item>
				<item>
			<title>Chromosome screening technique boosts IVF success</title>
			<link>http://www.phgfoundation.org/news/month/05/2012/#story_11798</link>
			<pubDate>Mon, 07 May 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ New results suggest that a new genetic screening test for embryos could significantly improve IVF success rates.  &amp;nbsp;  The test from Cambridge-based company Blue Gnome examined chromosomes from IVF embryos using an arrayCGH-based method, 24Sure.  &amp;nbsp;  Published in Molecular Cytogenetics, the n ... ]]></description>
		</item>
				<item>
			<title>Sequencing can boost genetic diagnosis for learning disability</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11759</link>
			<pubDate>Mon, 30 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ Efforts to identify genetic causes of learning disability suggest much higher rates of diagnosis may be feasible.  &amp;nbsp;  Learning disability and developmental delay are relatively common, affecting 1-3% of the general population, and genetic causes can underlie up to around half of all cases, depe ... ]]></description>
		</item>
				<item>
			<title>Translating genomics into health: meeting the challenges</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11694</link>
			<pubDate>Wed, 18 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ Registration has opened for an innovative event organised by the PHG Foundation, with a unique focus on the opportunities for genomics to improve population health, and the challenges of achieving the necessary transfer into health systems.  &amp;nbsp;  Translating Genomics, to be held in the city of Ca ... ]]></description>
		</item>
				<item>
			<title>Guidance on newborn screening for metabolic disorders</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11663</link>
			<pubDate>Thu, 12 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ The US Centers for Disease Control and Prevention (CDC) has issued new practice recommendations for newborn screening for inherited metabolic disorders.  The guidance in the Morbidity and Mortality Weekly Report notes the on-going challenges of maintaining high quality testing services as the number ... ]]></description>
		</item>
				<item>
			<title>US issues professional guidance on genomic testing</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11646</link>
			<pubDate>Wed, 11 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ The American College of Medical Genetics and Genomics (ACMG) has released a new Policy Statement on Genomic Sequencing.  Points to Consider in the Clinical Application of Genomic Sequencing sets out recommended guidelines for doctors highlighting situations where testing is likely to be most useful  ... ]]></description>
		</item>
				<item>
			<title>UK to pilot expanded newborn screening programme</title>
			<link>http://www.phgfoundation.org/news/month/04/2012/#story_11623</link>
			<pubDate>Tue, 10 Apr 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ The UK is to pilot an expansion of the national newborn screening programme, which detects rare genetic disorders via bloodspot screening of newborn babies.  &amp;nbsp;  Currently, the UK programme comprises just five conditions: phenylketonuria, congenital hypothyroidism, sickle cell anaemia, cystic fi ... ]]></description>
		</item>
				<item>
			<title>Oversight needed for clinical translation of genome-based tests</title>
			<link>http://www.phgfoundation.org/news/month/03/2012/#story_11528</link>
			<pubDate>Wed, 28 Mar 2012 00:00:00 +0100</pubDate>
			<description><![CDATA[ The Institute of Medicine (IOM) in the US has released a new report calling for an evaluation process to assess whether &amp;lsquo;omics-based&amp;rsquo; tests are valid and ready for clinical use.  &amp;nbsp;  Genome-Based Diagnostics: Clarifying Pathways to Clinical Use is the report from workshops on transla ... ]]></description>
		</item>
				<item>
			<title>Rapid growth of genetic testing in US despite lack of evidence</title>
			<link>http://www.phgfoundation.org/news/month/03/2012/#story_11452</link>
			<pubDate>Fri, 16 Mar 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ The US National Institutes of Health (NIH) has opened an online&amp;nbsp;Genetic Testing Registry (GTR), containing information on the availability, validity and usefulness of genetic tests provided by the test providers.  &amp;nbsp;  Plans for the GTR were announced last year (see previous news); it is int ... ]]></description>
		</item>
				<item>
			<title>Study on the personal impact of consumer genomics services</title>
			<link>http://www.phgfoundation.org/news/month/03/2012/#story_11393</link>
			<pubDate>Tue, 06 Mar 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ US researchers are leading a major project to examine the impact of direct-to-consumer personal genome sequencing  &amp;nbsp;  The Impact of Personal Genomics (PGen) Study, a major investigation into consumer genomics, is beginning data collection. 500 participants will be enrolled from each of two pers ... ]]></description>
		</item>
				<item>
			<title>New breast cancer gene identified</title>
			<link>http://www.phgfoundation.org/news/month/03/2012/#story_11366</link>
			<pubDate>Fri, 02 Mar 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ If these findings are reproduced in other populations, genetic testing for inherited causes of breast cancer might need to further expand to include mutations in this new gene, as well as other genes already implicated in the disease.&amp;nbsp;&amp;nbsp; ]]></description>
		</item>
				<item>
			<title>What's normal? Identifying harmful human gene inactivation.</title>
			<link>http://www.phgfoundation.org/news/month/02/2012/#story_11332</link>
			<pubDate>Tue, 28 Feb 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ Researchers have launched a new catalogue of &amp;lsquo;loss-of-function&amp;rsquo; (LoF) gene variants, which suggests that healthy individuals may have multiple completely inactive genes with no ill effects.  Part of the 1000 Genomes Project (see previous news) based at the Wellcome Trust Sanger Institute ... ]]></description>
		</item>
				<item>
			<title>Calls for expanded BRCA1 genetic testing of women</title>
			<link>http://www.phgfoundation.org/news/month/02/2012/#story_11295</link>
			<pubDate>Thu, 23 Feb 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ New research has suggested that UK guidelines on genetic testing for breast cancer may need to be updated.  &amp;nbsp;  Cancer Research UK (CRUK) scientists analysed over 300 women with triple negative (TN) breast cancer and identified BRCA1 mutations in over 10% of them.  &amp;nbsp;  Current NICE guidance  ... ]]></description>
		</item>
				<item>
			<title>Not enough evidence for genetic breast cancer tests</title>
			<link>http://www.phgfoundation.org/news/month/02/2012/#story_11275</link>
			<pubDate>Tue, 21 Feb 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ The UK's National Institute for Health and Clinical Excellence (NICE) has released a consultation document on the use of gene expression profiling as a guide to chemotherapy for breast cancer.  &amp;nbsp;  The diagnostics consultation reviews three gene expression profiling tests, MammaPrint, Oncotype D ... ]]></description>
		</item>
				<item>
			<title>Holistic approach to clinical cancer genomics in Norway</title>
			<link>http://www.phgfoundation.org/news/month/02/2012/#story_11197</link>
			<pubDate>Tue, 07 Feb 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ Norway has taken the first steps towards creating a national cancer genomic diagnostics service.  &amp;nbsp;  The first clinical applications of next-generation sequencing (NGS) technologies have been widely reported in the medical literature, and many hospitals around the world are trialing different f ... ]]></description>
		</item>
				<item>
			<title>Vision for future of genomics in UK health system</title>
			<link>http://www.phgfoundation.org/news/month/01/2012/#story_11079</link>
			<pubDate>Wed, 25 Jan 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ A new report from the government advisory body the Human Genomics Strategy Group (HGSG), Building on our inheritance, sets out a new strategic vision for how the UK can benefit from the adoption of genomic technologies in mainstream health services (see previous news).&amp;nbsp;    Genomics are said to  ... ]]></description>
		</item>
				<item>
			<title>Link between genetic variants and extreme old age confirmed</title>
			<link>http://www.phgfoundation.org/news/month/01/2012/#story_11062</link>
			<pubDate>Sun, 22 Jan 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ Research showing a key role for specific genetic variants in extreme longevity has been published in the open access journal PLoS ONE; the original paper was retracted from Science last summer (see previous news).&amp;nbsp;The revised paper repeats the original data analysis, excluding some genetic vari ... ]]></description>
		</item>
				<item>
			<title>Genetic embryo screening service to open in Ireland</title>
			<link>http://www.phgfoundation.org/news/month/01/2012/#story_11012</link>
			<pubDate>Wed, 18 Jan 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ An Irish fertility clinic is set to become the first in the country to offer genetic screening and pre-implantation genetic diagnosis (PGD) for serious conditions.  &amp;nbsp;  A new clinic in Dublin, established by the Beacon Medical Group in partnership with UK-based Care Fertility, plans to offer PGD ... ]]></description>
		</item>
				<item>
			<title>Major project to assess value of genomic medicine</title>
			<link>http://www.phgfoundation.org/news/month/01/2012/#story_10922</link>
			<pubDate>Mon, 09 Jan 2012 00:00:00 +0000</pubDate>
			<description><![CDATA[ PHG Foundation trustee Tim Aitman, professor of clinical and molecular genetics at Imperial College London, commented: &amp;quot;This is a trend that will definitely be found across the developed world in the coming two to five years&amp;rdquo; but cautioned that there were additional ethical and privacy is ... ]]></description>
		</item>
				<item>
			<title>Personalised genetic tests no more useful than family history</title>
			<link>http://www.phgfoundation.org/news/month/12/2011/#story_10775</link>
			<pubDate>Tue, 13 Dec 2011 00:00:00 +0000</pubDate>
			<description><![CDATA[ A new study published in Genetic Epidemiology has reported that genotyping provides no additional medical benefit over standard predictive information such as medical and family history.Researchers recruited over 3000 recipients of the Health Compass service from direct-to-consumer (DTC) genetic tes ... ]]></description>
		</item>
			</channel>
</rss>
