13 February 2007
The most recent edition of the English language Italian Journal of Public Health [Ital J Public Health 3(3-4)] is a special feature edition on Public Health Genomics, including an editorial on Public health genomics in Europe, and theme papers on various aspects of genomics, medicine and public health.
Huntington's disease. Walker FO (2007) Lancet 369(9557): 218-28. Full review including genetics and epidemiology, genetic testing and experimental treatments (PubMed).
Sorting out breast-cancer gene signatures. Massague J (2007) N Engl J Med. 356(3):294-7. Commentary accompanying report of a novel prognostic gene expression signature for different types of cancer, considering general prospects for clinical applications (PubMed).
Molecular signatures of lung cancer - toward personalized therapy. Herbst RS and Lippman SM (2007) N Engl J Med. 356(1):76-8. Editorial on another report of prognostic gene signature, this time for a form of lung cancer, and predicting future developments combining genomic, proteomic and clinical parameters to direct drug design and personalized therapeutics (PubMed).
Wilson's disease. Ala A et al. (2007) Lancet 369(9559):397-408. Review of this progressive genetic disease, which is caused by defective copper metabolism (PubMed).
National collaborative study groups: structure, benefits gained and potential for rare genetic diseases. Moore TB and McCabe ER (2006) Genet Med. 8(12):793-6. Commentary looking at the history of paediatric cancer trial groups as a model for establishing a similar study group for rare forms of genetic disease (PubMed).
Creating partnerships and improving health care: the role of genetic advocacy groups. Cody JD (2006) Genet Med. 8(12):797-9. Commentary based on personal experience of establishing the Chromosome 18 Registry and Research Society and on the benefits of creating such partnerships between clinicians and patients for different genetic conditions (PubMed).
The impact of CYP allelic variation on antidepressant metabolism: a review. Black Iii JL, O'Kane DJ and Mrazek DA (2007) Expert Opin Drug Metab Toxicol 3(1):21-31. Review of the pharmacogenomics of antidepressant medication (PubMed).