New reviews and commentaries, 17 January 2007

17 January 2007

In search of a familial cancer risk assessment tool. Kelly K and Sweet K (2007) Clin Genet 71(1):76-83. Review of web-based familial cancer risk assessment tools, and recommendations for the development of future tools (PubMed).

Sudden cardiac death in the young: a clinical genetic approach. Ingles J and Semsarian C (2007) Intern Med J 37(1):32-7. Review on the genetics of sudden cardiac death and the necessity for multidisciplinary clinical management of affected families (PubMed).

Polycomb silencing mechanisms and the management of genomic programmes. Schwartz YB and Pirrotta V (2007) Nature Genetics 8(1): 9-22. Review on the function of polycomb group complexes in epigenetic regulation (PubMed).

An evolutionary view of human recombination. Coop G and Przeworski M (2007) Nature Genetics 8(1): 23-34. Review looking at determinants of genetic recombination rates an d the implications for human genetics (PubMed).

Heterochromatin revisited. Grewal SI and Jia S (2007) Nature Genetics 8(1): 35-46. Review on the role of heterochromatin in different chromosomal processes (PubMed).

Dosage compensation: the beginning and end of generalization. Straub T and Becker PB (2007) Nature Genetics 8(1): 47-57. Review of sex chromosome dosage compensation mechanisms and implications for gene expression (PubMed).

The mouse as a model for human biology: a resource guide for complex trait analysis. Peters LL, Robledo RF, Bult CJ, Churchill GA, Paigen BJ and Svenson KL(2007) Nature Genetics 8(1): 9-22. Review on the availability and use of mouse genetics resources for complex genetic traits analysis (PubMed).

Innovations: Prenatal diagnosis: progress through plasma nucleic acids. DennisLo YM and Chiu RWK (2007) Nature Genetics 8(1): 71-76. Perspectives piece on the emergence of and prospects for using extracellular fetal nucleic acids for prenatal diagnosis (PubMed).

Genetic influences on preterm birth. Defranco E, Teramo K, Muglia L (2007) Semin Reprod Med 25(1):40-51. Review of the genetic contributions to the multifactorial condition of premature birth (PubMed).

Pharmacogenetics of cytochromes P450 in tropical medicine. Ribeiro V and Cavaco I (2006) Curr Drug Targets 7(12):1709-19. Review of the pharmacogenetics of P450 enzymes among ethnic groups in tropical regions (PubMed).

HMDB: the Human Metabolome Database. Wishart DS et al. (2007) Nucleic Acids Res 35:D521-6. Report on the database of human metabolic information, a resource for academic and clinical scientists, geneticists and nutritionists (PubMed).

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