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CAR-T cell therapy for lupusBlogCAR-T cell therapy involves genetically engineering T cells, a type of immune cell, so that they respond to a prespecified molecular marker, or antigen.
Are data trusts trustworthy?BlogData is vital to health innovation but there remains a common feeling of mistrust in those who hold that data. Dr Elizabeth Redrup Hill considers why and what can be done to engender greater trust.
Synthetic data in health-related researchUpdate: read the new paper 'High-fidelity synthetic patient data applications and privacy considerations' co-written by the authors of 'Are synthetic health data personal data?'
Evaluation of polygenic risk score applicationsReportHow current evidence is inadequate to determine clinical validity or utility of a polygenic score product in relation to its intended purpose and what is needed to resolve the gaps
Fragmentomics – the future of cfDNA testing?BlogOutlining the work of Prof. Dennis Lo and his team on the emerging science of fragmentomics.
Control of patient information in the COVID-19 eraReportThe ethical and legal considerations that need to be taken into account by policymakers should there be any future extension, or exception for COVID-19 purposes.
Implementing polygenic scores for cardiovascular disease into NHS Health ChecksReportWe evaluate the NHS Health Check programme as a possible exemplar for the introduction of the routine use of polygenic score analysis.