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What does ‘good governance’ look like for genome editing?
Blog 21 July 2021 In recent years, the potential to edit human genomes to treat or avoid genetic disease has been at the forefront of discussions about personalised medicine. However, using genome editing technologies is not just a questi...
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Somatic genome editing: an overview
Briefing Genome editing has featured frequently in the headlines and is a technology with the potential to revolutionise healthcare. Although a number of genome editing techniques are well established in research, the development...
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Somatic genome editing: promise and practicalities
Briefing The development of genome editing tools, including the discovery and refinement of CRISPR-based techniques and associated technologies, is fuelling a new wave of advances in genetic medicine. Somatic genome editing offer...
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Somatic genome editing: ethics and regulation
Briefing The therapeutic applications promised by a new generation of genome editing techniques, such as CRISPR, could have notable impacts on healthcare. However, enthusiasm for clinical genome editing must be tempered by r...
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Consultation response: developing global standards for governance and oversight of human genome editing
Consultation The PHG Foundation welcomes the WHO’s initiative to examine the scientific, ethical, social and legal challenges associated with human genome editing, and to make recommendations for governance mechanisms for both somati...
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Nuffield Council on Bioethics - Genome Editing Open Call for Evidence
Consultation The latest genome editing technologies provide faster, simpler and cheaper methods of selectively manipulating the genome.Although genome manipulation has been possible for decades, the accessibility of these new technol...
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Genome editing: a broad perspective on a precision technology
Blog 19 November 2019 Genome editing goes prime-time Genome editing was in the news again, following the publication of a paper that describes ‘prime-editing’, a new method of altering genetic information. Whilst more informati...
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From theory to therapy in the genome editing boom
Blog 21 August 2019 Last month, in her final annual report as Chief Medical Officer for England, Dame Sally Davies outlined the current status and future vision of UK involvement in global health. As a technology of global importance and co...
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Genome editing open call for evidence - updated response
Consultation Many of the same endpoints potentially possible using germline editing can be reached using currently available techniques that do not have the risks and uncertainties that are associated with germline editing,...
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Genome editing: promising, but beware the hype
Blog 14 June 2016 CRISPR-Cas9 is the genome editing technology that everyone is talking about, thanks to its relative low cost, speed and perhaps most of all ease of use. Together these elements are effectively democratising gene editing,...